57-Year-Old Woman With Fatigue and Lower-Extremity Edema

Abstract

A 57-year-old woman with a medical history of hypertension, type 2 diabetes mellitus with chronic kidney disease stage 3a, and coronary artery disease presented to the emergency department with a subacute history of progressive fatigue and bilateral leg swelling despite increasing doses of furosemide. Over the next several weeks, she reported feeling generally unwell with profound malaise, frequent urination, and increasing lower-extremity edema despite taking extra doses of her normal diuretic.