Abstract
Objective: An increasing number of patients are referred for TLE procedures due to lead failure. We evaluated the influence of selected factors on the incidence of electrical lead failure (ELF) in patients referred for TLE procedures. Methods: The study group consists of 300 patients qualified to TLE procedures due to various indications (24 patients with pocket infection, 35 patients with lead-dependent infective endocarditis, 241 patients with non-infectious indications). After exclusion of patients with lead dislocations there were 140 patients with ELF. The association between selected factors and ELF was assessed using the univariate and multivariate Cox proportional hazards model. Results: In the group of patients with ELF compared to control group (160 patients) there were significantly more women (41.4% vs 30.0%; p = 0.038), and patients had significantly better cardiac function (LVEF: 47.3% vs 38.4; p < 0.001, NYHA class: 1.69 vs 2.19; p < 0.001). Impact of selected factors on ELF evaluated in univariate and multivariate Cox proportional hazards model are presented in the table. Conclusion: It was confirmed both in univariate and multivariate analysis that the most significant factors influencing the incidence of ELF were cephalic vein cut-down as opposed to subclavian vein puncture and the presence of defibrillation lead.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
