55P Biodegradable and biocompatible 3D-printed scaffolds loaded with chemotherapy drugs: A new horizon for treatment of colon cancer with diffuse intraperitoneal metastasis

Abstract

Diffuse peritoneal metastasis is a big challenge in colorectal cancer patients. In this study, we used 3D printers to design biodegradable and biocompatible scaffolds loaded with doxorubicin. We believe sustained degradation of these completely degradable scaffolds in the peritoneal cavity can cause the sustained release of the drug in this cavity and decrease the drug's systemic side effects while increasing therapeutic efficacy.