Abstract

The objective of this study was to characterize the Luteolin composition and evaluate the antioxidant and anti-inflammatory activities of the Carex meyeriana Kunth extract. We got the dark green ethanol extract and the extraction rate is 5.15%. Analysis of Luteolin in Carex meyeriana Kunth extract was using HPLC, the concentration is 1.83%, and the data showed that is 4.7 times of Thyme extract. In the antioxidant activity, Carex meyeriana Kunth extract contains the total phenolic content (196.6 mg of gallic acid equivalents, GAE) in large amount and exhibited great DPPH free radical scavenging capacity (IC50 =58.86 ppm). The data showed the antioxidant capacity is higher than Gentian extract, Rhus chinensis Mill Chinese herbal extract and other Chinese herbal extracts. The superoxide radical scavenging rate of 1% Carex meyeriana Kunth extract was 0.40 mM trolox (trolox equivalent antioxidant capacity TEAC). The anti-inflammatory activity of Carex meyeriana Kunth extract was measured by 5-lipoxygenase inhibition assay (IC50 =277 ppm), and that is 1.14 times of Allantoin. Comprehensive results showed that the Carex meyeriana Kunth extract had the great potential in antioxidant and anti-inflammatory efficacy which could be used as a novel multi-function ingredient for cosmetic products.

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