555 A novel inhabitant of the wound microbiome promotes wound healing through IL-6-mediated re-epithelialization

Abstract

The skin microbiome exists at the interface of all cutaneous wounds, but microbial community constituents with the potential to confer a beneficial wound healing response are virtually unexplored. We previously performed a metagenomic analysis of diabetic foot ulcer samples and unearthed one such candidate microbe, Alcaligenes faecalis, which was the fourth most abundant species in the cohort but has scarcely been studied in the context of wounds. We found that treating murine diabetic wounds with A.