Abstract

An estimated 0.7% of the adolescent population experiences gender dysphoria. Some will seek gender-affirming hormone therapy. Transgender boys (those assigned female at birth who identify as male) take testosterone, typically as subcutaneous or intramuscular injections, to cause masculinization and achieve physiological levels of testosterone as seen in assigned males at birth. Testosterone may cause erythrocytosis. Current dosing guidelines are based on androgen therapy for adult hypogonadal cisgender men.

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