Abstract
BackgroundPerinatal asphyxia remains a challenging entity. NIRS offers a method to continuously monitor cerebral oxygen saturation.AimTo obtain insight into haemodynamic changes during hypothermia and rewarming in perinatal asphyxia using NIRS.MethodsWe...
Highlights
Background and Aims NeonatalHSV encephalitis is well described and known to cause morbidity
We report a case of vertically transmitted neonatal HSV-1 encephalitis and review existing literature on available treatment options (PubMed, EMBASE)
At 33.5°C FTOE had decreased to 0.20, cerebral rSO2 increased to 70%
Summary
HSV encephalitis is well described and known to cause morbidity. There is no consensus regarding its optimal treatment, especially around using suppressive oral therapy after intravenous acyclovir. We aim to discuss treatment controversies and review possible neurodevelopmental outcomes in such cases. NIRS offers a method to continuously monitor cerebral oxygen saturation. Aim To obtain insight into haemodynamic changes during hypothermia and rewarming in perinatal asphyxia using NIRS. Methods We report of an asphyxiated patient (37+6 weeks’, Apgar 6 and 8 at 1 and 5 minutes, first arterial blood gas pH of 6.67, base deficit –25). NIRS was started during the first hour of life and continued for a total recording time of 125 hours. We measured brain function using amplitude-integrated electroencephalography (aEEG).
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