Abstract
Literature suggests that social stressors (eg, peer problems) are associated with psychopathology in adolescence and that their associations are mediated by biological factors. Animal models of depression also suggest that stress is positively related to hypertrophy in the nucleus accumbens (NAcc), implicated in both reward and punishment processing. We aimed to examine a role of NAcc volumes in linking peer problems with depressive symptoms in adolescence. We hypothesized that peer problems are associated with altered NAcc volumes and that altered NAcc volumes are associated with depressive symptoms in adolescence.
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