Abstract

A method of obtaining an attenuation curve, and corresponding diffusion constant, from a single-shot procedure. In contrast to the conventional pulsed field-gradient spin echo (PGSE) procedures used to determine the diffusion attenuation curve of a body undergoing magnetic resonance imaging, the method uses a single-shot procedure. The procedure uses application of a single shot pulse sequence to initiate a spin-echo procedure. This procedure creates a number of gradient recalled echoes by alternating the diffusion gradient. Each subsequent gradient-recalled echo is attenuated by an additional pair of gradient pulses. This successive attenuation by the gradient pulses allows the diffusional attenuation curve to be determined accurately in a single procedure. Ratios of time symmetric echo pulses yield a value proportional to the diffusion constant.

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