Abstract
Background: Allergic colitis (AC) is a well recognised cause of rectal bleeding in infancy. Dietary antigens have been clinically implicated, in particular, cow's milk protein (CMP). The underlying immune mechanism remains elusive. The aim of the study is to characterise the systemic and gut mucosal T-helper type1/ type 2 (Th1/Th2) cytokine profile in infants with allergic colitis and, to correlate the clinical CMP sensitivity with in vitro response.
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