53 Factors Related to Pulse Pressure Changes In Routine Hemodialysis Patients In Dr Sardjito Hospital Yogyakarta

Abstract

Background and objectives: Pulse pressure (PP) has been shown as a risk factor for mortality and independent marker for thedevelopment of CVD inpatients on maintenance hemodialysis (MHD). The effect of change in PP during hemodialysisare associated with survival. The purpose of this study was to assess factors that associated with PP change in patients undergoing HD. Method: The study was conducted in hemodialysis care unit Dr. Sardjito teaching hospital in Yogyakarta, Indonesia. Cross sectional study design, involving routine hemodialysis patients. Sample collected by consecutive method. PP changed defined as PP = postdialysis minus predialysis pulse pressure. Results: This study included 184 patients; The average patient age was 50.79 ± 15.21 years old; among the patients, 57.1% were men and 54.2 % had diabetes. During the study mean PP = 1.72 ± 0.83; PP < − 5 = 96 (52.2%), PP −5 to +5 = 43 (23.4%) and PP> +5 are 45 (24.5%). The PP was significantly associated with age, HD duration, sex, blood fow rate, ultrafiltration, DM, neutrophil/lymphocyte ratio (N/L ratio) and albumin (Pearson chi-square, p < 0.05). Conclusions: Factors that associated with PP change in routine hemodialysis patients are age, HD duration, sex, blood fow rate, ultrafiltration, DM, inflammation and albumin. Modifying these factors may improve survival in the hemodialysis population.