Abstract

Aim: Genomic intratumor heterogeneity is an increasingly recognized phenomenon in various solid tumors. However, most methods are not designed to resolve the complexity of mixed cell populations. We have therefore developed the method of Multiparameter Ploidy Profiling (MPP). By applying this technology on tumor specimens from non-small cell lung cancer (NSCLC) we aim to decipher and genomically investigate all tumor populations (sharing same ploidy) present in the tumor specimens.

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