529 Poster - The psychosexual effects of risk reducing bilateral salpingooophorectomy in female BRCA1/2 mutation carriers: A systematic review

Abstract

Introduction: Breast and ovarian cancer account for approximately 15000 deaths per year in the United Kingdom. It is estimated that up to 20% of these cases have an inherited genetic aetiology. The most common genetic mutation occurs in the BRCA1 or 2 genes. For women with mutations in these genes, or a high incidence of breast and/or ovarian cancer in their family, riskreducing bilateral salpingo-oophorectomy (RRBSO) may be offered to eliminate the risk of primary ovarian cancer. In pre-menopausal women this results in immediate onset of surgical menopause. Women experience menopausal symptoms including hot flushes, vaginal dryness, loss of libido and dyspareunia. This article sought to explore the psychosexual impacts of risk reducing bilateral salpingo-oophorectomy in the published qualitative literature.