Abstract
Background Opsin3 is a non-visual opsin and is a member of the opsin family. Recent researchers found that opsin3 is highly expressed in human epidermal keratinocytes, melanocytes, hair follicles and fibroblast. However, it is rarely reported in human nevus cells. Objective To investigate whether opsin3 express in human nevus cells, nevus tissues, and 3D model of reconstructed nevus in vitro. Methods The expression of opsin3 in nevus tissues, paired adjacent normal skin tissues were analyzed by quantitative real-time PCR and western blotting.
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