Abstract
Genome-wide association studies have reported an association between genetic variants in or near the ANRIL (CDKN2B-AS1) gene and age-related diseases. Despite these variants’ proximity to CDKN2A, which encodes melanoma tumor suppressor genes, their associations with melanoma prognostic factors are unknown. Here we investigated the associations of these variants with primary melanoma Breslow thickness, ulceration, and tumor-infiltrating lymphocyte (TIL) grade. Our analysis included 3,285 European-origin participants in the Genes, Environment and Melanoma (GEM) Study with incident invasive primary melanoma.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
