(514) Are Intracorporal Injections Associated with Difficult Placement of Inflatable Penile Prosthesis Placement?

Abstract

Abstract Introduction Inflatable penile prosthesis (IPP) is the gold-standard treatment for erectile dysfunction that is refractory to pharmacologic therapies. While complications occur in 1-10% of patients, there remains a paucity of data regarding the impact of intracorporal injections (ICI) on a more difficult IPP placement. Objective We sought to demonstrate correlation between prior ICI and increased difficult with IPP placement. We hope to use our data to help guide future pre-procedural planning as well as patient counseling. Methods The records of patients who underwent IPP placement via single surgeon between 2016 – 2021 were retrospectively reviewed. Baseline patient demographics in addition to history of priapism, shunt, presence of Peyronie’s disease (PD), ICI use and duration, and intraoperative details including need for multiple corporal dilations and corporal scarring were gathered. Exclusion criteria included patients with re-operative/revision IPPs, patients with 2-piece IPPs, and patients with semi-rigid IPPs. The associations were calculated using Chi-squared analysis and logistic regression. Results There were 96 patients that met inclusion criteria, with average age of 62 years. Half (48/96) had history of ICI use, with mean duration of 17.25 months (range 1-65). ICI was not associated with corporal scarring (p=0.51) or need for multiple dilations during IPP placement (p=0.46). Duration of ICI (comparing subgroups of < 20 months and >20 months) was not significantly different with respect to corporal scarring (p=0.343) or need for multiple dilations (p=0.839). History of priapism or shunt was not associated with corporal scarring (p=0.251). Patients with PD were more likely to require multiple dilations (p=0.033). Conclusions History of ICI and its duration were not associated with corporal scarring and increased intraoperative difficulty. Patients with a history of Peyronie’s disease were more likely to require multiple dilations. Other studied factors including ICI duration of >20 months, history of priapism, and history of shunt are NOT associated with corporal scarring or need for multiple dilations. Disclosure Any of the authors act as a consultant, employee or shareholder of an industry for: Boston Scientific