Abstract
Traditional endoscopic surveillance of Barrett's esophagus (BE) suffers from a high rate of sampling error. Angle-resolved low coherence interferometry (a/LCI) is a non-invasive method of assessing neoplastic tissue. a/LCI obtains nuclear morphology measurements of epithelial tissues by combining the depth resolution of optical coherence tomography with the sensitivity to nuclear morphology of light scattering spectroscopy. We report the results of the first complete clinical in vivo study evaluating the use of a/LCI to assess BE.
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