Abstract

Deformability of red blood cells (RBC) plays an important role in determining the fluid mechanical properties of the blood. Important phenomena of blood flows in microcirculation depend on the combination of vessel geometry, RBC deformability and the collective behavior of RBC. Recently, we developed a computational model to analyze the dynamic behavior of RBCs in the blood flow using a spring network model based on the minimum energy principle. We also developed a large scale simulation method by using parallel computing technique. In the present study, a two dimensional simulation of multiple RBCs movement in a straight channel was conducted by using a massive parallel computer system and it was shown that the proposed model has a potential to represent the realistic behavior of multiple RBCs flowing in a microvascular vessel.

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