Abstract

ECP is an established therapy for CTCL yet patterns of utilization, complication rates, and outcomes vary widely among treatment centers. We hereby report our experience with 13 patients (pts) treated with ECP from 2013-2019; median age was 65 (range 47-87) years. All pts had advanced stage CTCL; 8 (61.5%) with mycosis fungoides (MF) and 5 (38.5%) with Sezary syndrome (SS). Median time from diagnosis to pheresis start was 2.8 months with a median of 2 lines of prior therapy. All pts initially started on a ECP regimen of 2 consecutive days per week with 8 (61.5%) pts concurrently using oral bexarotene (Bex) and subcutaneous interferon alpha (IFN), 2 pts on ECP alone (15.4%), 2 (15.4%) with Bex only, and 1 (7.7%) with IFN only.

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