50. Pineal mixed germ cell tumour: A case report and literature riview

Abstract

Introduction Primary germ cell tumour in the pineal region is very rare among all primary intracranial neoplasms, accounting for approximately 2% of these tumours. Mixed germ cell tumours are one of the six histologic subtypes which account for 10–13% of pineal germ cell tumours. Case report We present a case of mixed germ cell tumour in an 18-year-old male. He presented with a long history of confusion, memory loss, occasional headaches and diabetes insipidus. Neurological examination revealed Parinaud's syndrome. The MRI scan demonstrated a complex pineal region lesion with a large component of fat. Histologically, the tumour was shown to be a mixed germ cell tumour with germinoma accounting for greater than 95% and mature teratoma for less than 5% of the biopsies. Discussion In summary, a rare case of pineal mixed germ cell tumour is presented and the literature is reviewed.