Abstract
Background: Excessive proliferation of fibroblasts, which produce collagen, leads to Hypertrophic Scar (HS) formation in the wound healing process. 5-Fluorouracil (5-FU) is an anti-metabolic drug that inhibits fibroblast proliferation. The aim of this study was to determine whether 5-FU could help in reducing the healing time of wounds and HS formation in donkey skin.
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