Abstract

Reduction of benzo[c] [1,7]naphthyridin-4(3H)-ones with sodium borohydride in acetic acid led to a series of 5-ethyl-5,6-dihydrobenzo[c] [1,7]naphthyridin-4(3H)-ones. The latter are photostable fluorophores emitting in the green region of the visible spectrum with a fluorescence quantum yield of up to 0.43 and a Stokes shift of up to 133 nm, containing an “embedded” amino acid motif. The localization and photobleaching of the obtained compounds in cryosections of rat skin was studied.

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