Abstract
Abstract Early life stress is known to have a profound impact on the development and function of the gut and immune system in various species, including pigs. In particular, the process of weaning is a significant source of stress in pigs and has been shown to negatively affect gut health and immunity. This presentation aims to examine the current knowledge on the impact of early life stress, particularly weaning, on gut development and immunity in pigs with a focus on chronic inflammation as a driver of disease risk. The presentation will also compare the immune system and gut development between female and male castrates, highlighting the influence of biological sex on gut health. Additionally, new data on potential targets for gut inflammation will be presented. The findings of this presentation will be analyzed in the context of pig production and the implications for enhancing gut health and immunity throughout production. Overall, this presentation will provide a comprehensive overview of the current understanding of the impact of early life stress on gut development and immunity in pigs and highlights key areas for future research.
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