7-days of FREE Audio papers, translation & more with Prime
7-days of FREE Prime access
7-days of FREE Audio papers, translation & more with Prime
7-days of FREE Prime access
https://doi.org/10.1002/jmv.1890310402
Copy DOIJournal: Journal of Medical Virology | Publication Date: Aug 1, 1990 |
Citations: 3 |
Inoue-Melnick virus (IMV) synthesis in naturally infected human colon carcinoma cell lines can be enhanced by 5-bromodeoxyuridine (BUDR). The optimal conditions for BUDR enhancement differed between two cell lines, SW-480 and DLD-1. SW-480 cells produced 100 times more infectious IMV than DLD-1 cells by BUDR treatment. A clonal difference in IMV synthesis in SW-480 cells was also observed. The highest titer of virus was found in the culture fluid of clone H (SW-480/H) cells treated with BUDR, and a herpes-like virus was detected by negative-staining electron microscopy of concentrates of the culture fluid. One nonproducer clone (SW-480/B) was also activated to produce virus when treated with BUDR.
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.