Abstract
The overexpression of integrin αVβ3 enhances tumour development, metastasis, angiogenesis, treatment resistance, and clinical staging in breast cancer patients. As a result, inhibiting integrin αVβ3 might be a promising anti-cancer agent for breast cancer. Furthermore, dealing with a post-operative wound from breast cancer is difficult in cancer biology. The cancer-associated inflammatory proteins p70S6K and STAT3 are implicated in local recurrences of primary breast cancer in this regard. Hence, the present proposal is concerned with a new approach of integrin αVβ3-decorated nanocomposites for the intelligent subcellular targeted delivery of anticancer drugs and wound healing.
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