4-Fluorobenzonitrile

Abstract

[1194-02-1] C7H4FN (MW = 121.11 g mol−1) InChI = 1S/C7H4FN/c8-7-3-1-6(5-9)2-4-7/h1-4H InChIKey = AEKVBBNGWBBYLL-UHFFFAOYSA-N (reagent used in heterocycle synthesis, acylation, functional group interconversion, carbon–carbon insertion and cleavage, directed ortho-metalation, electrophilic aromatic substitution, hydration, reduction, amination, and nucleophilic aromatic substitution reactions) Alternate Names: 1-cyano-4-fluorobenzene, 4-cyanofluorobenzene, p-fluorobenzonitrile. Physical Data: mp = 32–34 °C, bp = 188 °C. Solubility: slightly soluble in H2O, soluble in toluene, DMSO, and most organic solvents. Form Supplied in: colorless crystals. Handling, Storage, and Precautions: the reagent is stable at room temperature and normal pressures. Avoid exposure to flame and heat since it melts quickly. Incompatible with strong oxidizing agents, strong acids, and strong bases. Toxicity (oral) rat LD50: >300 mg kg−1. After using, it must be stored and sealed tightly because it has an unpleasant odor.