Abstract
It is well established that cyclin D1 is an important component of estrogen regulation. We have previously reported that the transforming growth factor beta type I receptor (TβRI) is related to tamoxifen-sensitive tumors. In addition to TβRI, the type 2 receptor (TβRII) plays a key role in the regulation of TGF-β signaling.The aim of the present study was to explore the predictive value of cyclin D1/TβRII expression for the tamoxifen response in patients with hormone receptor-positive breast cancer.
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Schedule a callMore From: Annals of oncology : official journal of the European Society for Medical Oncology
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