Abstract

The transmembrane glycoprotein CD44, the major hyaluronan receptor, is considered to be involved in carcinogenesis. Its role as new therapeutic molecular target in solid tumors is under evaluation in clinical trials. The prognostic value remains controversial. Here, we aimed to investigate the correlation between CD44 expression and the clinicopathological features and survival of metastatic colorectal cancer (mCRC) patients (pts).

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