488 Assessment of myocardial systolic synchronicity using 3D multi-plane myocardial velocity imaging: comparison with 2D myocardial velocity imaging

Abstract

Background: Myocardial velocity imaging (MVI) has gained its acceptance in assessing systolic synchronicity by allowing to measure regional differences in the timing of systolic myocardial wall motion. To date, such studies were performed with subsequent 2D acquisitions, which might influence the data through changes in heart rate, loading and breathing. With the introduction of matrix array transducers, 3D multi-plane echocardiography has become feasible allowing single-beat assessment of all myocardial segments. The aim of this study was to assess the value of 3D MVI in measuring systolic synchronicity in comparison with 2D MVI. Methods: 11 healthy normals (EF> 55%, QRS duration 55%, QRS duration 140ms) were included. Apical 4-, 3and 2chamber views were acquired from all patients with 2D and 3D echo (Vivid7-Dimensions, GE, Horten, Norway). Peak systolic velocity (Vs), time to peak systolic velocity (Ts) were measured from 12 segments (6 basal, 6 mid). A tissue synchronicity index (TSI) was calculated, as the standard deviation of Ts. Vs, Ts and TSI measured with 2D and 3D MVI were compared using correlation and Bland Altman statistics. Results: The correlation coefficient (R), bias and the limits of agreement (LOA) between two methods for Vs, Ts, and TSI were as follows; Vs: R=0.80, bias=0.14cm/s, LOA= ±2.7cm/s, Ts: R= 0.66, bias=8.25ms, LOA= ±84ms and TSI: R= 0.99, bias=0.61ms, LOA= ±2.76ms. The regression analysis for TSI is shown the figure.