Abstract

Both amyloid light chain (AL) amyloidosis and transthyretin-related (TTR) amyloid have been viewed with reluctance to proceed with heart transplant. AL amyloid in particular has been a contraindation for heart transplant as the underlying disease process progresses. In the current era of proteasome inhibitors, AL amyloid patients may now be adequately treated and undergo heart transplant with subsequent bone marrow transplant. In our program, we have treated 7 AL amyloid patients who developed end-stage heart disease.

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