Abstract
Introduction: Hypo-attenuated leaflet thickening (HALT) - a marker of subclinical leaflet thrombosis commonly detected by cardiac computed tomography (CT) after transcatheter aortic valve implantation (TAVI) - may influence valve durability and function. We hypothesize that altered flow patterns in the aortic root as a consequence of commissural misalignment may contribute to the occurrence of HALT. Therefore, the purpose of this project was to compare the commissural alignment of the native and prosthetic aortic valves in cardiac CT in subjects with and without HALT and thereby identify potential predictors for subclinical leaflet thrombosis after TAVI.
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