477: Prenatal diagnosis of esophageal atresia type I and its impact on neonatal outcome

Abstract

Evaluate neonatal management and outcome of neonates with either a prenatal or a postnatal diagnosis of esophageal atresia (EA) type I. Population-based study using data from the French National Register for infants with EA born from 2008 to 2014. We compared prenatal and neonatal characteristics (until 1 year) amongst children with prenatal versus postnatal diagnosis of EA type I. 1118 live births with EA were recorded during the period, among which 88 (7.9%) were EA type I. Prenatal diagnosis was assessed in 75 cases (85.2%). Antenatal specialist counseling was done in 84.8% in the prenatal group. Gestational age at delivery in the prenatal group was significantly higher (36 weeks) than that in the postnatal subset (34 weeks; p = 0.048). Transfer after birth was less frequent in the prenatal group (14.9% vs. 92.3%, p < 0.0001). There is no difference regarding to the rate of gastrostomy, the delay between birth and the first intervention of reparation of EA and the length of first hospitalization. Stenosis was frequent in both subsets and was no significantly different (respectively 44.6% and 30.0%). The death rate was similar in the 2 groups (9.3% and 7.7%). Prenatal diagnosis is high in EA type I, allows antenatal parental counseling and avoids postnatal transfers. Cases with prenatal diagnosis are not more complicated at 1 year than those postnatally diagnosed.