Abstract

The presence of human leukocyte antigen (HLA) antibodies has been associated with cardiac allograft vasculopathy (CAV) after heart transplant (HT). The virtual crossmatch (VXM) involves quantification of HT candidate HLA specific antibodies and the subsequent avoidance of corresponding donor antigens. The purpose of our study was to compare the incidence of CAV at one year post HT between patients (pts) with positive panel reactive antibodies (PRA) who underwent VXM (VXM group) versus pts with 0% PRA, who did not undergo VXM (No VXM group).

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