46. Relationship between P Wave Dispersion and Left Ventricular Hypertrophy in Hypertensive Heart Disease Patients

Abstract

Background: It is associated with target-organ damage in various organs and ECG changes. P-wave durations and P-wave dispersion (PWD) are considered to reflect the heterogeneous conduction in atria. Objective: The aim of this study was to investigate relationship PWD and P-wave duration and left ventricular hypertrophy in hypertensive heart disease patients. Method: This study was a-single centre, retrospective study, included 55 consecutive patients with hypertension who had visited the cardiology clinic. Elektrocardiography (ECG) and transthoracal echocardiography (TTE) were performed. Patient were divided into LVH group and control group baed on TTE findings. Patients with valvular regurgitation (moderate or severe), valvular stenosis, myocardial infarction, LV dysfunction, pericardial disease, chronic obstructive pulmonary disease (COPD), bundle branch blocks, atrial fibrillation or flutter were excluded from the study. Results: We found 31 hypertensive patients (56%) had LVH by TTE. The mean age for the HHD was 57 ± 11 years while the control group was 56 ± 11. In the HHD group, maximum P-wave duration was significantly increased at 119.31 ± 13.60 ms, compared to 97.14 ± 18.20 ms in the control group (p < 0.001). There was also a significant increase in minimum P-wave duration in HHD group at 59.65 ± 15.56 ms, compared to control group with 53.33 ± 14.60 ms (p = 0.004). There was a significant increase in the PWD in the hypertensive group at 59.31 ± 19.62 ms, compared to controls with 43.80 ± 17.54 ms (p < 0.001). Conclusion: PWD was significantly increased in hypertensive patient with left ventricular hypertrophy.