Abstract
Reactive arthritis (ReA) is a term for a group of diverse inflammatory arthropathies in which the joint and extraarticular manifestations are caused by a preceding extraarticular infection with specific bacteria. ReA is sometimes included under the umbrella term spondyloarthritis, which refers to a group of heterogenous diseases characterized by arthritis, enthesitis, acute anterior uveitis, and human leukocyte antigen (HLA)-B27 positivity. ReA accounts for less than 2% of spondyloarthritis cases. ReA can be triggered by enteric, genitourinary, or pharyngeal infection with Streptococcus. The two forms of ReA after streptococcal pharyngitis are called rheumatic fever and poststreptococcal reactive arthritis (PSRA) and will be discussed separately from ReA from enteric and genitourinary infections.
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