Abstract
To date, no biomarkers for second-line anti-angiogenic treatment in RAS wild type (wt) metastatic colorectal cancer (mCRC) patients (pts) with progression after first-line anti-epidermal growth factor receptor (EGFR) agents have been validated. Data on dynamic change of circulating pro-angiogenic factors levels during treatment from the pre-planned interim analysis of DISTINCTIVE trial (NCT04252456) are presented.
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