453 P Wave duration and dispersion in mitral valve prolapse

Abstract

1 ; T. Seydaliyeva 1 1 Mustafa Kemal University, Cardiology Dept., Antakya/Hatay, Turkey Aims: P wave dispersion (PWD) is an electrocardiographic measurement, which reflects a disparity in atrial conduction and vulnerability to atrial fibril- lation. In this study, we compared P wave duration and PWD of mitral valve prolapse (MVP) patients with healthy control subjects. We also investigate the echocardiographic determinants of PWD in MVP patients. Methods and results: Sixty-nine MVP patients (mean age 36.1±12.4 years) and 32 healthy control subjects (mean age 35.2±10.9 years) were included in the study. Twelve-lead surface electrocardiography recording was ob- tained from all participants. The change in maximum and minimum P wave duration was measured manually and the difference between the two val- ues was defined as PWD. There was no difference between the two groups in terms of baseline demographic characteristics. Maximum P wave dura- tion was higher in MVP patients than controls (123.8±7.2 vs 115.3±6.1 ms, p=0.007). Minimum P wave duration was found to be similar in MVP pa- tients and healthy controls. Mean PWD value of MVP patients was found to be higher than those of controls (52.6±12.7 vs 46.2±9.1 ms, p=0.01). In patients with MVP, multiple regression analysis revealed that among the echocardiographic parameters that were tested, the echocardiographic degree of the prolapse, anterior mitral leaflet thickness, left atrial diameter and detection of mitral regurgitation were independently associated with PWD. Conclusion: P wave duration and PWD are increased in patients with MVP. PWD is related to the echocardiographic degree of the prolapse, anterior mitral leaflet thickness, left atrial diameter and detection of mitral regurgita- tion. The echocardiographic assessment may help to identify a subgroup of patients at increased risk of atrial arrhythmias.