448 Driver mutation analysis as a selective marker for immunotherapy in patients with pheochromocytoma and paraganglioma

Abstract

BackgroundMetastatic pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors associated with poor prognosis and limited therapeutic options. Recent advances in oncology-related immunotherapy, specifically targeting of the programmed death 1 (PD-1)/-ligand...