Abstract

Egfl7 is a chemoattractant for endothelial cells and its expression is restricted to endothelial cells. Hypoxia/reperfusion and CNI induced endothelial injury that occurs during and after transplantation incite the subsequent development of allograft vasculopathy. We investigated the effect of Egfl7 on endothelial cell intercellular adhesion molecule-1 (ICAM-1) expression in response to H/R injury and tacrolimus.

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