443 Risk of future coronary artery disease in women with medical complications in pregnancy

Abstract

Introduction and aims of the study: Women with medical conditions that arise in pregnancy are at higher risk for medical problems later on in life. 10% of women develop pregnancy induced hypertension/pre-eclampsia. Despite such women being classified as having a low risk for cardiovascular disease by scores such as the Framingham risk score, recent data (NICE) has clearly shown that these women unfortunately have an increased risk for cardiovascular disease. The aim of this study is to explore the link between pregnancies complicated pregnancies and cardiovascular disease. Method: A retrospective randomised case control study is being conducted non-pregnant women having coronary angiography +\- stenting. The cohort is still being expanded. Results: The average age of women included in the study is 43 years (standard deviation = 8.4). The current risk for angiographically detected coronary artery lesions in women who have had ischaemic heart disease (IHD) is 72% whilst women with no IHD have a risk of about 50%. Conclusions: Women having pregnancy induced hypertension (PIH) have a much higher relative risk for angiographical clinically significant lesions. This data supports the fact that women having PIH are at a higher risk of having IHD. This supports the growing need of obstetricians and gynaecologist to be well versed in the long term complications of medical complications in pregnancy. Adequate post-natal counselling has an important role in decreasing the morbidity and mortality later on in life.