Abstract
The prevalence of BRAF V600E in colorectal cancer (CRC) was about 10%. Despite recent therapeutic advances, BRAF V600E mutant CRC is still a challenge with a low response rate and suboptimal survival. Here we reported the safety and preliminary anti-tumor activity of vemurafenib and cetuximab in combination with FOLFIRI for BRAF V600E-mutated advanced CRC patients.
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