Abstract

Abstract Genome editing in the genetic stocks of food animals has tremendous potential as a tool for genetic improvement best suited to introduce traits not readily available for intensive selection in commercial breeding populations, especially those affecting disease resistance and adaptation to climate. To date, gene-editing has been used to alter prolactin receptor and produce heat-tolerant, registered Angus for commercial production of semen and embryos that rapidly improves efficient quality beef production in the tropics. More recently, genome alterations based on rationale design have been tested to demonstrate host resistance to porcine reproductive and respiratory syndrome virus and bovine viral diarrhea virus in swine and cattle, respectively. This presentation will highlight the results of these new traits to breed healthier commercial animals that will eventually change global market dynamics of livestock production.

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