436 Is the preterm rupture of membranes before 24 gestational week the lethal disorder?

Abstract

Introduction and aims of the study: Preterm rupture of membranes (PPROM) occurs in 2-3% of pregnancies, but there are only a few studies about PPROM before 24 weeks. Some reports described the lethality of this condition, probably due to an immature respiratory system and difficulties with its development due to oligohydramnios. The study aimed to assess the neonatal outcomes in fetuses with early onset of PPROM. Methods: It is a single-centre retrospective cohort study. A database of 48419 singleton deliveries between 2010 and November 2020 was created using anonymized electronic patient records of Saint Sophia’s Hospital in Warsaw, Poland.