430P Prediction of pathologic complete response to preoperative (chemo)radiotherapy and/or chemotherapy in rectal cancer using clinical and imaging parameters

Abstract

Complete pathological response (pCR) is achieved in 10-20% of rectal cancers when treated with preoperative short-course radiotherapy (scRT) or long-course chemoradiotherapy (CRT) and in 28% with total neoadjuvant therapy (TNT) including scRT/CRT with chemotherapy. pCR is linked to better outcome. Which clinical or imaging factors predict pCR?.