43. CORRELATION BETWEEN SERUM CREATININE AND HEMOGLOBIN LEVEL IN CHRONIC KIDNEY DISEASE PATIENT WITH HYPERTENSION: STUDY ON PRE-HEMODIALYSIS PATIENT AT RSUD ULIN BANJARMASIN

Abstract

Background: Chronic kidney disease (CKD) is a failure of kidney function due to structural abnormality that occurs for at least 3 months with or without the decrease in glomerular filtration rate (GFR) of less than 60 ml/min/1.73 m2. Hypertension is the leading cause of CKD and commonly found with prevalence ranges from 60%–90% depends on the stage of CKD. People with CKD often experience anemia as the kidney function worsens. Meanwhile, it has been known that the increase of hemoglobin level will affect to the increase of systolic and diastolic blood pressure. Objective: The purpose of this study was to analyze the correlation between serum creatinine and hemoglobin levels in CKD patients with hypertension at RSUD Ulin Banjarmasin. Methods: This study is analytical observational with cross sectional approach. The samples of this study consist of 40 pre-hemodialysis patients who meet the inclusion criteria at RSUD Ulin Banjarmasin between July–September 2019. The serum creatinine level and hemoglobin level were compared. Results: The result of this study showed the mean level of serum creatinine was 10.31 mg/dL and the mean level of hemoglobin was 7.85 g/dL. The correlation between serum creatinine and hemoglobin level was tested using Spearman correlation test and showed p value = 0.023 and r value = −0.318. Conclusions: There is a significant and weak negative correlation between serum creatinine and hemoglobin level in CKD patients with hypertension at RSUD Ulin Banjarmasin.