Abstract
There are three main cascades - WNT, Hedgehog and NOTCH, occur in cancer stem cells during the cancerogenesis. However, the conducted studies indicate the existence of other signaling mechanisms of regulation - NF-kB and PI3K signaling pathways. In our work, we investigated the expression of NF-kB, PI3K, PTEN molecules, as well as WNT, Hedgehog, NOTCH in cells of triple negative and HER-2 overexpressed breast cancer with high and low content of cancer stem cells (positive and negative ALDH1A1 expression).
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
