Abstract
Gastroesophageal reflux disease (GERD) is an important risk factor for chronic allograft dysfunction in lung transplant (LTx) recipients. Diagnosis currently relies on invasive tests such as oesophageal pH probe testing. We have previously reported pepsin in exhaled breath condensate (EBC) as a potential marker of aspiration and this has also been studied in bronchoalveolar lavage (BAL) but the correlation between the two is unknown. The aim of this study was to study the correlation between EBC and BAL pepsin in the investigation of GERD post LTx. We also investigated the correlation between these measures and acid exposure on pH probe testing.
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