Abstract
In the title isoquinolinedione compound, C16H16N2O3S, the piperidine ring in the tetrahydroisoquinoline ring system adopts a half-boat conformation. The essentially planar thiazole ring [maximum deviation = 0.007 (2) Å] makes a dihedral angle of 34.49 (7)° with the mean plane through the tetrahydroisoquinoline ring system. In the crystal structure, two neighbouring molecules are linked via pairs of O—H⋯N and C—H⋯O hydrogen bonds into inversion-related dimers incorporating R 2 2(9) hydrogen-bond ring motifs. These dimers are further linked by weak intermolecular C—H⋯π interactions.
Highlights
In the title isoquinolinedione compound, C16H16N2O3S, the piperidine ring in the tetrahydroisoquinoline ring system adopts a half-boat conformation
Two neighbouring molecules are linked via pairs of O—H N
C—H O hydrogen bonds into inversion-related dimers incorporating R22(9) hydrogen-bond ring motifs. These dimers are further linked by weak intermolecular C—H interactions
Summary
USM, Penang, Malaysia, and bSchool of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, People’s Republic of China. R factor = 0.041; wR factor = 0.135; data-to-parameter ratio = 8.9. In the title isoquinolinedione compound, C16H16N2O3S, the piperidine ring in the tetrahydroisoquinoline ring system adopts a half-boat conformation. The essentially planar thiazole ring [maximum deviation = 0.007 (2) Å] makes a dihedral angle of 34.49 (7) with the mean plane through the tetrahydroisoquinoline ring system. Two neighbouring molecules are linked via pairs of O—H N and C—H O hydrogen bonds into inversion-related dimers incorporating R22(9) hydrogen-bond ring motifs. These dimers are further linked by weak intermolecular C—H interactions. For the stability of the temperature controller used for the data collection, see: Cosier & Glazer (1986).
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