42. INTRADIALYTIC HYPERTENSION AND SIX MONTH – ALL CAUSE MORTALITY IN HEMODIALYSIS PATIENTS

Abstract

Background: Hemodialysis is safe and beneficial for CRF patient. However, there are several complications during hemodialysis process including intradialytic hypertension (IDH). IDH has been associated with poor outcomes in hemodialysis patients. But only a few studies have investigated the relationship of IDH with mortality in patients undergoing hemodialysis. Objective: This study aims to determine the relationship between IDH and 6 month-all cause mortality in hemodialysis patients. Method: The cohort design study was carried out in October 2019 to March 2020 at the Hemodialysis Unit of Roemani Muhammadiyah Hospital Semarang. The dependent variable was IDH that defined as rise in Mean Arterial Pressure (MAP) >15 mmHg within or immediately post dialysis. The mortality was investigated over 6 months after the baseline measurements. Result: Among 85 respondents, it was found that 22 (25.9%) respondents categorized into IDH group and 63 (74.1%) categorized into non IDH group. The respondents consisted of 54 (63.5%) males and 31 (36.5%) females. The mean delta MAP in the IDH and non IDH group was (mean ± standard error, 22.6 ± 7.9 vs −5 ± 12.3). From the Kaplan Meier survival curve described that non IDH group had higher survival rate than the IDH group (96.8% vs 77.3%, p = 0.004). From Cox regression study we found a significant relationship between IDH and 6-month all cause mortality in hemodialysis patients (p = 0.018; Hazard ratio: 7.305). Conclusion: There was a significant relationship between IDH and 6 month – all cause mortality in hemodialysis patients.