Abstract
Objective: To explore the relationship of postnatal catch-up growth and insulin sensitivity. Methods: Fasting glucose, insulin and HOMA value in 44 small for gestational age (SGA) infants and 74 appropriate for gestational age (AGA) infants at age 3 month were studied by a prospective study, and the relations with catch up growth were analyzed in 44 SGA infants. Results: SGA infants had significantly higher fasting insulin concentration and HOMA value than did AGA infants. Adjustment for gestation, there was a negative association between velocity of catch-up growth and insulin concentration and HOMA value in SGA infants (P < 0. 05). 12 non-catch-up growth in weight and length infants had significantly higher fasting insulin concentration and HOMA value than did they on the third day after birth in SGA group respectively [ insulin : (21. 92 ±14. 25) mU /L vs (11. 08 ±9. 59) mU /L P < 0. 05 ; HOMA : (4. 15 ±2. 96) vs (1. 86 ±1. 71), P < 0. 05 ]. Conclusions: Catch-up growth is closely related with insulin sensitivity in early postnatal life, and poor growth might result in worse insulin sensitivity in SGA infant s during that time.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
